Recent publications


Peripheral NOD-like receptor deficient inflammatory macrophages trigger neutrophil infiltration into the brain disrupting daytime locomotion.

Victoria Kwon, Peiwen Cai, Cameron T. Dixon, Victoria Hamlin, Caroline G. Spencer, Alison M. Rojas, Matthew Hamilton and Celia E. Shiau. Communications Biology (2022).

Read here.

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Zebrafish harbor diverse intestinal macrophage populations including a subset intimately associated with enteric neural processes.

Graves, C., A. Chen, V. Kwon and C. E. Shiau. iScience (Cell Press)(2021).

Read here.

Brain-localized and Intravenous Microinjections in the Larval Zebrafish to Assess Innate Immune Response.

Rojas, A. M. and Shiau, C. E. (2021). Bio-protocol 11(7): e3978. DOI: 10.21769/BioProtoc.3978.

Check out the paper here.

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Liposomal Clodronate-mediated Macrophage Depletion in the Zebrafish Model.

Yang, L., A.M. Rojas, and C. E. Shiau (2021). Bio-protocol 11(6): e3951. DOI: 10.21769/BioProtoc.3951.

Drainage of inflammatory macromolecules from the brain to periphery targets the liver for macrophage infiltration. 
Linlin Yang, Jessica A Jiménez, Alison M Earley, Victoria Hamlin, Victoria Kwon, Cameron T Dixon, Celia E Shiau. eLife (2020)

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Critical role for a subset of intestinal macrophages in shaping gut microbiota in adult zebrafish.

Earley, A. M., Graves, C. L., and C. E. Shiau. Cell Reports 2018  Read paper here.

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Genetic analysis of zebrafish homologs of human FOXQ1, foxq1a and foxq1b, in innate immune cell development and bacterial host response.

Earley, A., C. Dixon, and C. E. Shiau. PLoS One. 2018 Mar 13;13(3):e0194207. doi: 10.1371/journal.pone.0194207. eCollection 2018.

PMID: 29534099 Free PMC Article

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An anti-inflammatory NOD-like receptor is required for microglia development.

Shiau CE, Monk KR, Joo W, Talbot WS. Cell Rep. 2013 Dec 12;5(5):1342-52. doi: 10.1016/j.celrep.2013.11.004. Epub 2013 Dec 5.

PMID: 24316075  Free PMC Article

Screen Shot 2016-02-06 at 7.28.07 PMDifferential requirement for irf8 in formation of embryonic and adult macrophages in zebrafish.

Shiau CE, Kaufman Z, Meireles AM, Talbot WS. PLoS One. 2015 Jan 23;10(1):e0117513. doi: 10.1371/journal.pone.0117513. eCollection 2015.

PMID: 25615614  Free PMC Article

Screen Shot 2016-02-06 at 7.30.29 PMThe phosphate exporter xpr1b is required for differentiation of tissue-resident macrophages.

Meireles AM, Shiau CE, Guenther CA, Sidik H, Kingsley DM, Talbot WS. Cell Rep. 2014 Sep 25;8(6):1659-67. doi: 10.1016/j.celrep.2014.08.018. Epub 2014 Sep 15.

PMID: 25220463  Free PMC Article

An effective assay for high cellular resolution time-lapse imaging of sensory placode formation and morphogenesis.

Shiau CE, Das RM, Storey KG. BMC Neurosci. 2011 May 9;12:37. doi: 10.1186/1471-2202-12-37.

PMID: 21554727  Free PMC Article

Altering Glypican-1 levels modulates canonical Wnt signaling during trigeminal placode development.

Shiau CE, Hu N, Bronner-Fraser M. Dev Biol. 2010 Dec 1;348(1):107-18. doi: 10.1016/j.ydbio.2010.09.017. Epub 2010 Sep 27.

PMID: 20883685  Free PMC Article

N-cadherin acts in concert with Slit1-Robo2 signaling in regulating aggregation of placode-derived cranial sensory neurons.

Shiau CE, Bronner-Fraser M. Development. 2009 Dec;136(24):4155-64. doi: 10.1242/dev.034355.

PMID: 19934013  Free PMC Article

Robo2-Slit1 dependent cell-cell interactions mediate assembly of the trigeminal ganglion.

Shiau CE, Lwigale PY, Das RM, Wilson SA, Bronner-Fraser M. Nat Neurosci. 2008 Mar;11(3):269-76. doi: 10.1038/nn2051. Epub 2008 Feb 17.

PMID: 18278043
Cover of March 2008 Volume 11 No 3